The Yeast Exploration Tool Integrator (YETI) is a novel bioinformatics workbench for the visualisation and analysis of functional genomic data sets from the budding yeast Saccharomyces cerevisiae.

YETI effectively integrates genomic, gene expression, protein interaction and functional annotation data sets together, enabling users to visualise and analyse these different data sets in an integrated and modular fashion. YETI consists of a number of independent sections for the visualisation of chromosomes, hierarchically clustered gene expression data, protein interaction networks, and a database section for searching through functional and annotation data. However, all of the sections are closely inter-linked enables users to select features of interest in one section and seamlessly move into another section where data relevant to their selection will be automatically highlighted and displayed. This is combined with a group or systems approach that enables users to select an entire group of genes, such as all the genes involved in a particular biological process or pathway, enabling them to investigate the dynamics of how these genes are working together. In addition, YETI has a number of advanced visualisation functions such as the ability to overlay gene expression data sets onto entire chromosomes and protein interaction networks.

YETI was initially designed as a proof-of-concept workbench to demonstrate the effectiveness of bringing together various functional genomic data sets in one tool for integrated visualisation and analysis. YETI has since proved to be a useful tool for the assignment of functionality to individual genes in a guilt-by-association approach, in reconstructing entire biological pathways based purely on the experimental data, as well as in investigating the intricacies of broad biological processes by utilising the group approach.